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AMIKACIN INTERMEDIATE 40371-50-4 CBZ-L-HABA

AMIKACIN INTERMEDIATE 40371-50-4 CBZ-L-HABA

99% up by HPLC, medical grade
  • Product Details

Product Information


Product name

Amikacin intermediate 262368-30-9

Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy Butyric (CBZ-L-HABA)

Molecular Formula

C12H15NO5

Molecular Weight

253.25

CAS No.

40371-50-4

Quality Standard

99% up by HPLC, medical grade

Appearance

White powder


COA of Amikacin Intermediate 40371-50-4


ITEMS

SPECIFICATION

RESULTS

DESCRIPTION

WHITE OR OFF-WHITE SOLID POWDER

OFF-WHITE SOLID POWDER

MELTING RANGE

75.0℃-79.0℃

76.0℃-78.5℃

LOSS ON DRYING

≤1.0%

0.12%

SPECIFIC ROTATION

-3.5°to -7.0°

-4.75°

ASSAY

≥98%

99.15%

RESIDUE ON IGNITION

≤1.0%

0.05%

CONCLUSION

CONFORMS TO THE ENTERPRISE STANDARD

STORAGE

AIRTIGHT, PROTECTED FROM LIGHT, IN COOL AND DRY PLACE.


Usage


Amikacin intermediate 262368-30-9(Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy Butyric (CBZ-L-HABA)) is a key intermediate of Amikacin. Amikacin is an aminoglycoside antibiotic, a white or off-white powder or a crystalline powder; almost odorless and tasteless. Its mechanism of action is to act on ribosomes in bacteria, inhibit bacterial protein synthesis, and destroy the integrity of bacterial cell walls, causing bacterial cell membrane destruction and cell death. Suitable for infections caused by Gram-negative bacilli and penicillin-resistant Staphylococcus aureus.

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NMN
NICOTINAMIDE MONONUCLEOTIDE 1094-61-7
Product Information β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. Name Nicotinamide Mononucleotide Alias BETA-NICOTINAMIDE MONONUCLEOTIDE;   NMN;β-D-NMN; BETA-NMN; NICOTINAMIDE RIBOTIDE; Nicotinamide nucleotide; Nicotinamide mononucleotide; NICOTINAMIDE MONONUCLEOTIDE; NicotinaMide Ribonucleotide; B-NICOTINAMIDE MONONUCLEOTIDE; BETA-NICOTINAMIDE MONONUCLEOTIDE CAS NO. 1094-61-7 Molecular Formula C11H15N2O8P Quality Standard with High Purity 98.0%min Grade Standard Food grade  / 98% min Package Size 1kg/bag, 5kg/bag, or as per customers’ requirements. Usage 1. Nicotinamide mononucleotide in human cells play an important role in energy generation, it is involved in intracellular NAD (nicotinamide adenine dinucleotide, cell energy conversion important coenzyme) synthesis, used in anti-aging, fall blood sugar and other health care products. 2. Nicotinamide Mononucleotide is a water-soluble vitamin, The product is white crystalline powder, odorless or nearly odorless, bitter in taste, freely soluble in water or ethanol, dissolvable in glycerin. 3. Nicotinamide Mononucleotide is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role. In addition, nicotinamide has prevention and treatment of heart block, sinus node function and anti-fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil. COA of Nicotinamide Mononucleotide Items Specification Results Appearance White to pale yellow crystalline powder White crystalline powder Appearance of solution (5% w/v in water) Colorless to pale yellow and clear Colorless and clear Water ≤6.0% 0.5% Arsenic ≤1 PPM < 1 PPM Lead ≤1 PPM < 1 PPM Mercury ≤1 PPM < 1 PPM Heavy Metal ≤10 PPM < 10 PPM Assay(Dry basis) 97.0% - 100.0% 98.1% Conclusion: The product conforms with the enterprise standard.
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