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IMATINIB MESYLATE 220127-57-1

IMATINIB MESYLATE 220127-57-1

In-house Standard
  • Product Details

Product Information


Product name

Imatinib Mesylate

Molecular Formula

C30H35N7O4S

Molecular Weight

589.71

CAS No.

220127-57-1

Quality Standard

In-house standard

Appearance

White powder


COA of Imatinib Mesylate


TEST ITEMS

SPECIFICATION

RESULTS

Appearance

White or slightly yellow crystalline powder, 
homogeneous and with fine grain size. 
No foreign particles are observed.

Slightly yellow crystalline Powder

Solubility

Soluble in water and in acids solutions, slightly soluble 
in methanol insoluble in acetone, acetonitrile and 
dilute hydroxyl alkaline solution

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Identification

Complies

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Water

≤1.0%

0.8%

Heavy metals

≤20ppm

10ppm

Melting range

212 – 220℃

214-216℃

Residue on ignition

≤0.1%

0.08%

Particle size

90% < 100 μm

50% < 50 μm

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Bulk density

NLT 0.4g/ml

0.6g/ml

Chromatographic

purity

Individual impurities: ≤0.2%

Total impurities: ≤0.5%

0.16%

0.32%

Assay

98.5%-102.0% of Imatinib mesylate,

calculated on anhydrous basis.

99.70%

Residual solvents

Ethyl acetate: ≤5000ppm

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Acetone: ≤5000ppm

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N,N-Dimethylformamide: ≤880ppm

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Methanol: ≤3000ppm

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Dichloromethane: ≤300ppm

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We provide you with high-quality imatinib mesylate powder and imatinib mesylate price乐虎国际娛乐 is very reasonable and competitive.


Usage


Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, 
乐虎国际娛乐 the causal agent in chronic myelogenous leukemia.


As an inhibitor of PDGFR, imatinib mesylate appears to have utility in the treatment of a variety of 
乐虎国际娛乐 dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.


乐虎国际娛乐 1. a tyrosine kinase inhibitor. highly specific for bcr-abl, the enzyme associated with chronic myelogenous leukemia (cml) and certain forms of acute lymphoblastic leukemia (all)

2. echinocandin antifungal, active against infections with aspergillus and candida, inhibits cell wall synthesis

乐虎国际娛乐 3. anticancer

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